The mishap took place near Runnisaidpur village as the driver lost control over the bus, they said.
Two persons, identified as Rambabu Singh and Nawal Baitha, natives of neighbouring Muzaffarpur district, died on the spot, while the injured persons were admitted to a Primary Health Centre (PHC) where the attending doctors referred six seriously injured persons to the Srikrishna Medical College and Hospital (SKMCH) for treatment, they said.