Two Shramik Special trains carrying more than 2,100 migrant workers left on Tuesday night from Kalyan junction in neighbouring Thane district, the Central Railway (CR) said.
One of them, carrying nearly 1,200 migrants, left for Darbhanga in Bihar, a CR release said.
The end-to-end service departed at 8.37 pm carrying only the registered and nominated passengers cleared by the Maharashtra government, the release said.
The second end-to-end Shramik special train left for Guntakal (Andhra Pradesh) around 11 pm, carrying nearly 930 migrants, according to Railway officials.
On Monday, the Central Railway had operated two Shramik special trains between Akola-Lucknow and Bhiwandi- Jaipur.