The "Rack City" hitmaker's friend and employee Henderson, died on Wednesday. Police sources said the 29-year-old bodyguard was behind the wheel when he collided with another vehicle, reported TMZ.
He got out of his SUV to check on the people in the other car, only to be knocked down and killed by another passing motor.
Tyga's representative said the star is "devastated, shocked, and heartbroken" by the tragedy.
And the 26-year-old rapper - who is dating Kylie Jenner - also paid tribute to his friend on Instagram.