MTA has already garnered international interest with academies looking to open in the Middle East, Australia, France, West Africa and China.
Tyson held the record of being the youngest boxer to win the WBA, WBC and IBF heavyweight titles at the age of 20.
The 50-year-old Tyson will be revealing more about the venture on May 4 to be followed by the launch on May 6.
Asked why he chose Dubai to make this announcement, Tyson said the city has established itself on the world map by hosting many leading sporting events and icons, besides attributing it to the residents' obsession with fitness.
The American boxing icon added, "I am positive that this is going to be only the beginning of a long-running successful association between myself and the region.