The band scrapped plans to perform in the French capital the night after the atrocities, which included a massacre at an Eagles of Death Metal show at the Bataclan.
They played the first rescheduled show on Sunday evening, reported BBC.
"We stand together with the families of those killed in Paris," said Bono, as victims' names were projected on a huge video screen at the AccorHotels Arena.
"We stand together with the families of those killed in San Bernardino," he added.