Being developed by health giant VPS Healthcare group, one of the leading healthcare providers in India and Middle East, the new hospital will be the first private facility in the UK to offer Proton Beam Therapy - a type of radiotherapy that uses sub-atomic particles to attack cancer cells with less damage to surrounding tissues than conventional radiotherapy.
Proton beam therapy is currently generally unavailable through the NHS (National Health Service), though a small number of UK patients are sent abroad for the treatment if their care team believes they are ideally suited to it.
The facility will open in 2017 with a bed capacity of 150 and will be supported by around 2,000 staff in jobs ranging from administration, support and service roles to leading specialist healthcare professionals.
The new 'super-speciality' cancer treatment will be available at the hospital through the NHS from 2018.
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"VPS Healthcare has been encouraged by the UK Government's ongoing policy to support health and pharmaceutical companies, and we believe that our investment in this dynamic sector will not only ensure that we play a key role in supporting this initiative, but will also help to grow and develop the next generation of medical breakthroughs," said 38-year-old Vayali, the youngest recipient of the Pravasi Bharatiya Samman Award in 2014.
VPS Healthcare is recognised as a Global Growth Company by the World Economic Forum and is also a member of the MENA Regional Partnership Community of the WEF.
The company is holder of the Guinness World Record for largest Simultaneous Self-Examination for Breast Cancer.
Welcoming the investment, the Mayor of London Boris Johnson said: "This is tremendous vote of confidence in London's thriving life sciences sector as well as the skills and talent of our amazing healthcare professionals.