The announcement comes as four other major banks are expected to fined billions of dollars for rigging the foreign exchange market in settlements with US and British regulators.
The US Department of Justice dropped charges against UBS into the currency rigging probe, and granted it conditional immunity for cooperating with the authorities, the bank said in a statement.
It will nevertheless pay a USD 342-million penalty (307 million euros) to the US Federal Reserve and change the way its foreign exchange system works, the bank said.
UBS said it had agreed to plead guilty to one count of wire fraud for conduct in the LIBOR matter, pay a USD 203-million fine and accept a three-year term of probation.
UBS was fined 1.4 billion Swiss francs (USD 1.49 billion, 1.33 billion euros) in 2012 by Swiss authorities for its part in manipulating the benchmark rate.
The regulators verdicts on American giants JPMorgan Chase and Citigroup, British banks Barclays and Royal Bank of Scotland are expected to fall today.