Jamie and Crystal Roberts in Staffordshire were horrified when they found the creepy crawlies, believed to be Brazilian Wandering Spiders which are the world's deadliest spiders, in the bananas they had bought from a local corner shop.
Jamie, 31, had spotted white patches covering the fruit and assumed it was harmless mould.
But when he took a closer look later he realised the bananas were infested with a spider nest containing hundreds of spiders.
Jamie fled his home, along with his wife Crystal, 30, and two children on the advice of the pest controllers, 'mirror.Co.Uk' reported.
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Pest controllers told the family they suspected the creatures were the deadly Brazilian Wandering Spiders.
They are considered the most toxic spiders on Earth and their venom is said to be 30 times more powerful than that of a rattlesnake.