Forty two-year-old Tracey Kinder put her own life at risk by giving her grandson, who was born with a rare liver condition, part of her organ.
"The doctors told me I had a chance of dying in the operating-theatre or after surgery but they couldn't stop me. Nothing anyone could say would have changed my mind," Kinder said.
Kinder has made medical history by becoming the first grandparent liver donor, the 'Daily Express' reported.
The baby named Reuben was born with a rare liver condition, a form of biliary atresia, in which the bile ducts become blocked.
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"Reuben couldn't have gone on much longer. When they opened him up they said his old liver had almost stopped functioning," his mother Beth Kinder, 26, said.
Tracey, from Goole, East Yorkshire, stepped forward when other possible donors, including Reuben's father were told a liver donation from them would not work.
Up to 40 per cent of child liver transplants in the UK are donated by relatives. Surgeons prefer to use parents and younger family members as donors because grandparents are older and likely to be less fit.