"The Secretary-General condemns the horrific terrorist attack at the Radisson hotel in Bamako which killed an unknown number of civilians and injured many more," a statement issued by his spokesperson said here.
Gunmen stormed the Radisson Blu hotel in Bamako, the capital of the West African nation of Mali, taking more than 100 hostages.
At least 22 people have been killed in the attack and many others injured.
Ban noted with concern that the attacks are taking place at a time when the peace process is making good progress and the signatory groups to the Agreement on peace and reconciliation in Mali were in Bamako to attend the sixth meeting of the Comite de suivi de l'Accord (CSA) with the Malian Government and international partners.
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"The Secretary-General deplores any attempt to derail the implementation of the Agreement. He expresses his full support to the Malian authorities in their fight against terrorist and extremist groups," the statement added.
The attack comes less than a week after ISIS terrorists carried out one of the most audacious attacks in Paris killing 130 people.
The United Nations Multidimensional Integrated Stabilization Mission in Mali (MINUSMA) has been assisting the Malian authorities in the handling of this crisis.
The United States and French special forces also assisted in freeing the hostages.
The Mission said it is currently supporting Malian authorities and is providing security back-up while also deploying medical resources at the site.
Mali has been riven by conflict since a military coup d'etat in 2012, resulting in very large scale internal and external displacement in the region.