Ramzy Ezzeldin Ramzy said his boss, UN envoy Staffan de Mistura, was in discussion with warring parties to organise "direct negotiations", a departure from past rounds where the sides met separately with moderators.
The UN is working "with a view to holding these talks hopefully in the next few weeks."
De Mistura's recent target dates to relaunch talks have all been missed, amid a failure to contain the fighting.
While the UN has said it would clearly be preferrable to host talks with a ceasefire in place, future negotiations should not have preconditions.
Regardless of the setbacks, the UN "will never give up on the political process" to end Syria's five-year war, he added.
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