China's ministry of state security detained Sandy Phan-Gillis in March and she is being investigated on accusations of "spying and stealing state secrets", according to the website savesandy.Org, which provides information on her and her case.
Phan-Gillis was held while crossing the border to Macau at the end of a visit to China by a trade delegation from the Texas oil capital Houston, where she is a member of the mayor's International Trade and Development Council, the site said.
"Sandy is not a spy or a thief," her husband Jeff Gillis said on the website.
It was not clear why the case had not been publicised until yesterday, when the first announcements were posted to the site.
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But the news came as Xi embarked on a visit to the United States beginning with a stop in Seattle before heading to Washington for talks with President Barack Obama.
"Sandy has now been detained for over six months, and she has not been allowed to see or speak with friends, family, or even her lawyers in that time," the website says.
"Chinese authorities have conceded that they don't have sufficient evidence to file formal charges against Sandy, yet they have not released her," it added.
Phan-Gillis has family origins in southern China but was born in Vietnam, the website says, leaving the country in the late 1970s as part of the exodus of "boat people" who fled Communist rule.
Other foreign citizens have run afoul of China's powerful security officials.
Feng Xue, a Chinese-born US geologist who spent more than seven years in a Chinese prison after being convicted on state secrets charges, was released in April and deported.
A Canadian Christian couple who ran a coffee shop in the Chinese border city of Dandong, and had aided Christians fleeing North Korea, were detained on espionage charges last year.