The man is hospitalised in Indiana with Middle East respiratory syndrome, or MERS, according to the Centers for Disease Control and Prevention, which is investigating the case along with Indiana health officials.
Saudi Arabia has been the center of an outbreak of MERS that began about two years ago. At least 400 people have had the respiratory illness, and more than 100 people have died. All had ties to the Middle East or to people who traveled there. Infections have been previously reported among health care workers.
The MERS virus has been found in camels, but officials don't know how it is spreading to humans. It can spread from person to person, but officials believe that happens only after close contact. Not all those exposed to the virus become ill.
But it appears to be unusually lethal, by some estimates, it has killed nearly a third of the people it sickened. That's a far higher percentage than seasonal flu or other routine infections. But it is not as contagious as flu, measles or other diseases. There is no vaccine or cure for MERS.
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CDC officials say they are sending a team to investigate the man's illness, his travel history and to track down people he may have been in close contact with.
Saudi Arabia health officials have recently reported a surge in MERS illnesses; cases have tended to increase in the spring. Experts think the uptick may party be due to more and better surveillance. Researchers at Columbia University have an additional theory, there may be more virus circulating in the spring, when camels are born.