President Donald Trump promptly accepted his resignation and designated Don J Wright to serve as Acting Secretary, effective at 11:59 pm (local time) on September 29, 2017, the White House said in a statement.
"I'm not happy, okay? I can tell you, I'm not happy," Trump told reporters before he boarded Marine One at White House for Air Force One at Andrews Air Force Base on his way to New Jersey.
Price, 62, resigned after a series of damaging reports about use of an expensive charter plane to do official business. On Thursday he cut a check of over USD 50,000 for the cost of his seat. However, media reports said the entire plane cost the government more than USD 1 million. Before becoming the Health Secretary, he was a Republican Congressman from Georgia.
Price was also unable to push Trump's agenda of repealing Obamacare.
More From This Section
Indian-American Seema Verma, who has been playing a key role in repeal and replace of Obamacare and has won accolades from Trump multiple times is seen as a strong contender for the Cabinet position of Health and Human Services.
Currently administrator of the Centers for Medicare and Medicaid Services, Verma hails from Indiana the home State of Vice President Mike Pence.
In just eight months since Trump took office, he has fired or lost his chief of staff, chief strategist, national security adviser, press secretary, two communications directors, a deputy chief of staff, a deputy national security adviser, the FBI director and many other aides and advisers.