The proposed agreement would solve a major logistical hurdle facing the US as it pulls out the bulk of its combat forces and gear from Afghanistan over the next year.
Under the arrangement, troop flight operations would shift to Romania from Manas airbase in Kyrgyzstan, where a lease expires in July 2014, US defense officials told AFP.
The tentative plan will be discussed today when Pentagon chief Chuck Hagel hosts Romania's Defence Minister Corneliu Dobritoiu for talks, said two Pentagon officials, who spoke on condition of anonymity.
The logistics of the US withdrawal are "phenomenally complicated," the official said. "And this was a key piece of the puzzle."
Also Read
The possible agreement reflected "a growing relationship between the United States and Romania, which is in a strategically vital part of the world," he added.
Romania previously agreed to host a site for US anti-missile interceptors as part of a NATO ballistic missile defense system.
Representatives from both governments in recent months have been negotiating the terms for use of the Mihail Kogalniceanu air base in eastern Romania, which would serve as the main hub for flying troops out of Afghanistan back to the United States.
Five US military personnel are currently stationed at the air base and the number of American troops and contractors would dramatically increase if the agreement goes ahead. In Kyrgyzstan, about 1,500 US troops and contractors work at the air base.
The Manas air field in Kyrgyzstan has been a recurring headache for Washington with tense negotiations over rental fees.
In 2010, political unrest in the Central Asian country led the US military to temporarily limit flights at Manas.
The United States has about 51,000 troops in Afghanistan and the bulk of the force will be pulled out -- along with huge quantities of vehicles and weapons -- by the end of 2014.
Withdrawing soldiers and equipment out of land-locked Afghanistan is a daunting logistical challenge, and the Pentagon plans to rely mainly on land routes through Pakistan to move out most of the vehicles and gear.