The five Russians were targeted under the Magnitsky Act, passed by Congress in 2012 in response to the death of Russian lawyer Sergei Magnitsky.
He died in prison after exposing a tax fraud scheme involving Russian officials, and the law named after him allows the US to target violators of human rights. All told, the US has targeted 49 Russians under that law.
The latest additions include Ramzan Kadyrov, the head of Chechnya, a predominantly Muslim republic in southern Russia.
The Treasury Department also said it was targeting a Chechen law enforcement official, Ayub Kataev, for alleged involvement in abuses this year against gay men.
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The United Nations and human rights groups have decried reports that men suspected of homosexuality have been rounded up in Chechnya and in some instances killed.
"We will continue to use the Magnitsky Act to aggressively target gross violators of human rights in Russia, including individuals responsible for extrajudicial killings, torture and other despicable acts," said John Smith, a top sanctions official at the Treasury Department.
Magnitsky was a Russian lawyer hired by Hermitage Capital, a hedge fund owned by British citizen William Browder.
After accusing Russian officials of carrying out a USD 230 million tax fraud, he was charged with tax evasion and put in prison, where he died in 2009 at 37. An official Russian probe blamed a heart attack, but Russia's presidential council on human rights concluded he'd been beaten and denied medical treatment.
The sanctions law became a sore point between the US and Russia after it was signed into law by former President Barack Obama. Shortly after, Russian President Vladimir Putin signed a law banning American citizens from adopting Russian children, in a move widely viewed as retaliation.
The sanctions freeze any assets the individuals may have in the United States, and also bar Americans from doing any business with them.
In 2016, the Magnitsky Act was expanded to allow the US to target human rights abusers anywhere, not just in Russia. The Trump administration is expected to target additional individuals under that law in the coming days.
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