The print edition of the Venezuelan anti-government daily El Nacional will appear for the last time Friday, shutting down due to a mixture of political pressure and a crippling economic crisis that left it unable to source newsprint.
The presses of the 75-year-old daily will fall silent after two decades of confrontation with the leftist governments of Hugo Chavez and his successor, President Nicolas Maduro, during which dozens of media outlets have been closed down.
"They have managed to silence radio and television and have made the independent print media disappear," said Miguel Henrique Otero, the newspaper's chairman who in editorials regularly slammed Maduro as a dictator.
The newspaper will continue its criticism of the socialist government via a website.
"It was impossible to continue financing the paper," editor Argenis Martinez told AFP.
El Nacional has faced serious problems since 2013, when the government created a company that monopolized the import and sale of newsprint.
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More than half the 134 newspapers then in circulation in Venezuela were forced to close, according to a press freedom group, Espacio Publico.
The National Union of Press Workers has slammed an "escalation" of attacks on the press as Maduro cracked down on opposition to his socialist government following deadly street protests last year.
In 2017, 52 radio stations and eight television channels - including the local CNN Spanish service - went off the air.
"It's a great pain, but it's a pain that we were preparing for," the paper's arts editor Hilda Lugo told AFP. "We held out longer than we thought we would be able to."