Freddy Guevara, the opposition-stacked National Assembly's number two official, sought refuge at Chile's embassy in Caracas after the pro-government dominated Supreme Court's announcement Friday.
Chile's foreign ministry said in a statement that Guevara, 31, was received at the residence of its ambassador "as a guest," and that he "had requested the protection of Chile" based on "what he considers to be imminent threats to his security and personal integrity."
The prominent opposition leader became the sixth Venezuelan to seek protection at the embassy in under three months, including four judges who are already protected in Chile and a fifth who has remained at the diplomatic residence since April.
The pro-government constitutional assembly -- which governs crisis-stricken Venezuela with absolute power -- is meanwhile investigating the lawmaker in connection with mass protests against the embattled President Nicolas Maduro that left 125 dead between April and July.
Spain has rejected the measures taken against Guevara, while the so-called Lima Group -- comprised of 12 American states -- described it as "a new attack against the rule of law and the division of powers in Venezuela.