While demonstrations were mostly calm elsewhere in the socialist South American country, an anti-government march turned violent in this restive city near the border with Colombia, which was an epicenter of the 2014 movement.
Embattled President Nicolas Maduro, meanwhile, yesterday said his administration foiled a coup attempt that was supposed to take place yesterday and he alleged it had US backing.
He said five air force officers, including a general, were detained for plotting to use a military jet to bomb the presidential palace. He provided no evidence or other details.
A sea of protesters marched in San Cristobal's streets. Some youths covered their faces with bandanas and threw projectiles at police officers clad in riot gear, who fired tear gas canisters while onlookers ran in the opposite direction with young children in their arms.
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At least five people were injured in the fighting, San Cristobal Mayor Patricia Gutierrez said.
Young protesters in Caracas set up a flaming barricade to shut down the main thoroughfare of a wealthy neighborhood where much of last year's protesting was centered. As dusk fell, some youths threw Molotov cocktails at police, who responded with rubber bullets.
In a different part of town, a larger number of government supporters marched in a demonstration of support for embattled President Nicolas Maduro.
Dozens of government buses could be seen at the start of the route, indicating some marchers were government workers brought in by officials.