Fighting in the war rages despite an August agreement, and food experts have repeatedly warned parts of South Sudan's northern Unity region are on the brink of famine.
"Alarming reports of starvation, acute malnutrition and catastrophe levels of food insecurity have been reported in areas worst affected by the ongoing violence," the Food and Agriculture Organisation (FAO) said in a statement.
It warned of "a bleak forecast" for the rest of year, with "rapidly depleting food supplies and a likely protracted lean season", adding that "food prices have reached record highs."
"Food insecurity has spread to areas previously considered relatively stable, highlighting the cumulative impact of conflict, economic downturn and climactic shocks," FAO added.
Fighting has spread to previously largely peaceful Western Equatoria and Western Bahr el Ghazal regions, bread basket areas for the rest of the country.
"Increased fighting puts the upcoming agricultural season at risk, with alarming potential to impact on food security for the entirety of South Sudan," FAO added.
The monitors also called for rebel leader Riek Machar to return to take up his post of vice-president.
"There are no remaining difficulties in the return of the First Vice President-designate and the formation of the new transitional government of national unity," said Festus Mogae, who heads the Joint Monitoring and Evaluation Commission (JMEC).
Civil war began in December 2013 when President Salva Kiir accused his former deputy Machar of planning a coup, setting off a cycle of retaliatory killings that have split the poverty-stricken, landlocked country along ethnic lines.
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