Almost 1,000 people with lower back pain and around 350 with knee osteoarthritis were recruited for the Australian-based research.
Weather data from the Australian Bureau of Meteorology were sourced for the duration of the study period.
Researchers from The George Institute for Global Health compared the weather at the time patients first noticed pain with weather conditions one week and one month before the onset of pain as a control measure.
"Human beings are very susceptible so it's easy to see why we might only take note of pain on the days when it's cold and rainy outside, but discount the days when they have symptoms but the weather is mild and sunny," said Maher.
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Results showed no association between back pain and temperature, humidity, air pressure, wind direction or precipitation.
The findings reinforce earlier research on back pain and inclement weather from The George Institute which received widespread criticism from the public on social media.
"People were adamant that adverse weather conditions worsened their symptoms so we decided to go ahead with a new study based on data from new patients with both lower back pain and osteoarthritis," said Maher.
"The results though were almost exactly the same - there is absolutely no link between pain and the weather in these conditions," Maher added.
"People who suffer from either of these conditions should not focus on the weather as it does not have an important influence on your symptoms and it is outside your control," said Manuela Ferreira from The George Institute.
"What's more important is to focus on things you can control in regards to managing pain and prevention," said Ferreira.
The study appears in the journal Pain Medicine.
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