Numerous women came forward to accuse Weinstein of sexual harassment and misconduct in the wake of exposes from The New York Times and The New Yorker.
"It has been a shocking and yet remarkable experience. I applaud the courage of these women and men who have come forward with stories of abuse and harassment," Stewart told Variety.
The 77-year-old actor said "victimising, controlling and stigmatising" young women has been the norm of Hollywood for decades.
"I've never been involved in anything as a victim or as an antagonist, but one was aware that bad things were generally happening from time to time. Yet there was an atmosphere of insecurity and fear and an unwillingness by people to deal with it properly," he said.
"Now thanks to the courage of women and men who are coming forward almost daily, we can change things," said Stewart.
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