West crushed South by eight wickets at the Sardar Patel stadium in Motera, while East stunned defending champions North by nine wickets with at the Motera B stadium.
Electing to bat first, South were bowled out for 70 in 17.4 overs with the spin duo of Taus Rizvi (4-11) and Eithram Ali (3-6) causing maximum damage.
Roshan Thyagrajan (22) was the only batsman to cross the 20-run mark in an otherwise disappointing showing by the South batting line-up.
In the other match of the day, Tauhid Talukdar's superb all-round show helped East start off their campaign with a win.
He took three for seven with the ball and contributed 33 with the bat as East won with 58 deliveries to spare.