The top eight teams in the International Cricket Council ODI rankings at the end of September 2017 automatically advance to the event in England. The West Indies -- struggling in ninth spot three points behind Pakistan and a further two adrift of Bangladesh -- have only this series, a return duel in England in September and, critically, three matches against Pakistan in the Caribbean in April to make the cut.
England's brand of ultra-aggressive limited-over cricket since the disappointment of the 2105 World Cup, where they failed to get past the group stage, makes them favourites to extend their domination of the home team.
West Indies' last victory in a head-to-head series was in 2007 in England under the leadership of Chris Gayle, one of several prominent players now ruled ineligible for regional representative duty due to commitments to lucrative T20 franchise tournaments around the world.
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- Ongoing disputes -
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While most of the frontline batsmen were able to get decent scores in a commanding performance on Saturday, they laboured on the same pitch at Warner Park two days later, eking out a two-wicket win after the middle-order stuttered against the spinners.
With the surface at the Sir Vivian Richards Stadium in North Sound expected to be of a similar nature, West Indies are likely to play both frontline slow bowlers, Devendra Bishoo and Ashley Nurse.
West Indies cricket's ongoing disputes involving premier players continues as batsman Dwayne Bravo, who publicly disparaged West Indies Cricket Board president Dave Cameron via Twitter last November and was subsequently withdrawn from the tour of Zimbabwe, is not being considered for selection until he submits a formal apology.
England have no such issues to contend with and will have a batting line-up at full strength with the exception of Alex Hales, who has recuperated well enough from injury sustained in India but will not be considered for selection for the two matches in Antigua. He is however likely to be in the frame for the series finale in Barbados on March 9.
West Indies: Jason Holder (captain), Kieran Powell, Evin Lewis, Kraigg Brathwaite, Shai Hope (wicketkeeper), Jason Mohammed, Rovman Powell, Carlos Brathwaite, Ashley Nurse, Devendra Bishoo, Shannon Gabriel.
England: Eoin Morgan (captain), Jason Roy, Sam Billings, Joe Root, Jos Buttler (wicketkeeper), Ben Stokes, Moeen Ali, Chris Woakes, Adil Rashid, Liam Plunkett, Steven Finn.