"We will ensure that the safety and livelihoods of people are not jeopardised in our pursuit of nuclear power," Singh said at a function to confer lifetime achievement awards on four nuclear scientists.
Noting that the 2011 Fukushima incident had raised "justifiable" concerns on atomic energy, Singh said, "Even as we implement our power programme, we will continue to ensure that nuclear power remains wholly safe."
He said Parliament was examining a Bill to set up a new Nuclear Safety Regulatory Authority.
The Prime Minister said India has enhanced its cooperation with the International Atomic Energy Agency and the first Operational Safety Review Team recently visited the Rajasthan Atomic Power Station.
"As we pursue our national growth objectives to meet the rising aspirations of our people, the supply of affordable clean energy will be one of our foremost national challenges and a key priority for our government. Nuclear energy will remain an essential and increasingly important element of our energy mix," he said.
Singh said India was in the process of expanding its indigenous nuclear power programme.
On the much-delayed Kudankulam nuclear power project, he said: "We will reach a new milestone soon, as the first nuclear reactor with Russian collaboration at Kudankulam starts operating, with the second reactor to follow later in the current year."