The 10-match event will take place over a three-week period from June 6 to June 26, the West Indies Cricket Board (WICB) announced.
Matches will be played in Guyana, St Kitts and Barbados.
"This tournament promises to be very exciting with two of the world's top teams coming to the Caribbean," said Roland Holder, the WICB manager for cricket operations.
"It will provide a golden opportunity for our team to test themselves against two of the best sides in the world in the ODI format."
The series then moves to the Barbados capital of Bridgetown for the final round of matches at Kensington Oval, culminating with the final.