The original film was directed by Tim Burton and starred Michael Keaton and Alec Baldwin in lead roles.
The actress confirmed about the film on Monday's "Late Night with Seth Meyers", reported Entertainment Weekly.
"Um, I think I can confirm it, because Tim Burton did this interview - like, it was very hush hush, top secret... And then he was doing some press for Big Eyes and he did an on-camera interview and he said, 'Oh yeah we're doing it and Winona's going to be in it,' and I was like (shocked face)."