Amid the volatile atmosphere in Britain, the banks are outwardly keeping a straight face.
"We are locked down on this," said Michael Duvally, spokesman for Goldman Sachs, when asked how his bank is preparing for the possibility that Britain's anti-Europe camp will win in the referendum on Thursday.
Morgan Stanley and Bank of America gave identical responses.
But in stark contrast, the Wall Street offices of the lawyers who work for the banks are almost under a state of alert, with every option under review, according to banking industry sources speaking anonymously.
Also Read
If the Brexit measure goes through, it could lead to Britain's losing huge benefits of freely trading with Europe. No longer would US banks be able to easily handle all of their business, broking, lending or other, in EU countries from London.
After public opinion polls were proven to be greatly unreliable in recent British elections, the banks are not putting their faith in any of the reported results, or even conducting their own private polls.
JPMorgan Chase has already reserved hotel rooms for traders close to its offices.
Call centers dedicated to communications with clients have been put into place, several banks confirmed.
"Thursday is going to be a hectic day. We are expecting large movements," one banker said.
"Our clients are worried about what's going to happen with the pound. Forex is the biggest concern."
The five big US banks employ more than 40,000 people in London, more than in all of the rest of Europe.
A vote to leave the EU "would be a negative for the US universal banks since costs could increase and capital markets activity could weaken," analysts at investment bank KBW wrote in a recent report.