The incident was reported from a hotel in Paharganj.
The victim has been identified as Shazia, a resident of Brahmpuri in north-east Delhi.
Her husband Rashid, who brought her to the hotel and booked a room for them yesterday, is absconding. Rashid had recently divorced her but had entered into a compromise and brought her back.
The incident came to light when hotel staff became suspicious as the room was found locked from inside. Rashid was seen going outside in the morning.
Police was informed and they broke open the room only to find Shazia strangled.
Investigators said they were scanning the CCTV footages of the hotel for clues.