Yadav ran into the reigning champion Jordan Burroughs of USA in the second round where he was summarily matted 0-7, halting the Commonwealth Games gold medallist's run in the competition.
Earlier, Yadav made a resounding start as he overcame Russia's Kakhaber Khubezhty 10-2 in the opening bout.
2011 World champion Burroughs proved his might over the 24-year-old Indian by decimating him 0-7.
Vinesh has an easy first bout and defeated Mexico's Wendy Martinez 7-0 but failed to overcome Isabelle in an enticing battle.
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Vinesh opened her account as she was awarded a caution point but soon her opponent gained the upper hand by completing a back hold (two points) and finished the first three-minute period with a 2-1 advantage.
The Indian started off well in the second period and collected a two-point take down to gain a lead but the Senegal girl soon wrested the advantage in her favour with another back grip on the Vinesh.