Shares tumbled Monday in Europe and Asia after China announced sharp increases in the number of people infected with a potentially deadly virus.
In Paris, the CAC 40 lost 1.9 per cent to 5,907.40 while Germany's DAX skidded 1.7 per cent to 13,342.32.
Britain's FTSE 100 gave up 2.2 per cent to 7,421.93.
Shares also looked set for declines on Wall Street, where the future contracts for the S&P 500 and the Dow Jones Industrial Average both sank 1.2 per cent.
China announced it was extending its week-long public holiday by an extra three days as a precaution against having the virus spread still further.
By midnight Sunday, the National Health Commission said 80 people had died out of 2,744 cases that were confirmed.
More From This Section
Various governments have announced plans to evacuate people from Wuhan, the central Chinese city at the center of the pandemic.
China halted outbound tours and Wuhan and some other cities stopped public transport, obliging tens of millions of people to stay where they are at the time of the country's peak travel season.
Many Asian markets, including China's, were closed for Lunar New Year holidays, while Australia was closed for Australia Day.
Tokyo's Nikkei 225 index sank 2 per cent to 23,343.51.
India's Sensex lost 1 per cent to 41,204.15, while the benchmark in Thailand dropped 3.1 per cent.
Indonesia's share benchmark was 1.8 per cent lower.
Traders who would be typically discussing the weekend football results are now sadly focusing on mortality scores this morning," Stephen Innes of AxiCorp said in a commentary.
Apart from the direct impact on tourism and travel, any economic shock to China's colossal industrial and consumption engines will spread rapidly to other countries through the increased trade and financial linkages associated with globalisation," he said.
The virus that has spread to a dozen countries in addition to Hong Kong and Macau can cause pneumonia and other severe respiratory symptoms.
The World Health Organisation has not yet declared the situation a global emergency, which would bring more money and resources to fight it, but could trigger still more economically damaging restrictions on trade and travel.
In other developments in Asia, the Indian government said it plans to sell its entire stake in the national carrier Air India to shore up falling revenues and privatize the airline.
A government document issued Monday invited initial expressions of interest in the airline, after an initial attempt to sell the carrier last year failed to attract a single bidder.
Air India operates both domestic and international routes, has a debt burden of more than 580 billion rupees (USD 8 billion) and has been operating at a loss for years.
On Friday, the S&P 500 had its worst day since early October, dropping 0.9 per cent as health care stocks saw steep losses.
The sell-off followed news that a Chicago woman had become the second US patient diagnosed with the new virus from China.
The Dow Jones Industrial Average dropped 0.6 per cent and the Nasdaq composite lost 0.9 per cent.
The yield on the 10-year Treasury fell to 1.64 per cent from 1.74 per cent Thursday.
Investors have been shifting money into safe-play, high-dividend stocks and US government bonds.
The surge in bond-buying has sent yields lower.
The yield on the 10-year Treasury note fell to 1.62 per cent from 1.67 per cent late Friday.
Investors also are digging through the latest batch of company earnings reports, including strong results from chipmaker Intel and American Express.
This week is shaping up to be the busiest week for earnings, with roughly 40 per cent of the companies in the S&P 500 due to issue their results for the last three months of 2019.
Benchmark US crude gave up USD 1.85 to USD 53.34 per barrel in electronic trading on the New York Mercantile Exchange.
It lost USD 1.40 to USD 54.19 per barrel on Friday.
Brent crude, the international standard, declined USD 1.98 to USD 57.91 per barrel. It shed USD 1.39 to USD 59.89 per barrel on Friday.
In currency trading, the dollar weakened to 108.87 Japanese yen from 109.28 yen. The euro fell to USD 1.1020 from USD 1.1025.