After recovering yesterday as airline and travel stocks rebounded from falls caused by the deadly Brussels attacks, European markets headed south once more ahead of the Easter break, with miners taking a hit also, on falling metals prices.
Earlier, Asian stocks were hit by the stronger dollar which piled pressure on the outlook for commodity sales, with Chinese equities also hurt by weak earnings.
Wall Street opened its Thursday session lower with dealers citing weak oil, a strong dollar and the latest US durable goods orders figures as factors for the downturn.
News that consumer confidence in Germany is beginning to feel the heat from global economic risks and a poorer retail picture in Britain added to the downbeat sentiment, traders said.
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In foreign exchange, the euro dropped against the dollar.
"The dollar continues to strengthen and this remains one of the key reasons that commodities are under pressure," said Brenda Kelly, analyst at traders London Capital Group.
In London, the share prices of mining group Anglo American and Rio Tinto fell sharply, and oil majors also fell.
The picture had been the same in Asia after crude prices tumbled on news that US commercial stockpiles surged by 9.36 million barrels last week, more than three times the amount forecast by analysts.
Hints the US could raise interest rates next month meanwhile drove the dollar higher, piling further pressure on commodities and sending Sydney's resources-rich benchmark stocks index sliding 1.1 per cent.
A stronger greenback makes it more expensive for investors using other currencies to buy dollar-priced commodities, and raw materials from iron ore to gold took a hit.