India's leg-spin twins Kuldeep Yadav and Yuzvendra Chahal shared five wickets among them in an impressive bowling show but du Plessis ensured that the Proteas have a competitive total on board after opting to bat.
Du Plessis scored his eighth ODI hundred after a half- empty Kingsmead Stadium bore witness to South Africa's top- order collapse. The hosts lost four wickets for 51 runs before du Plessis and Chris Morris (37) rescued them with a 74-run partnership for the sixth wicket.
For India, Yadav took 3/34 and Chahal returned 2/45 as the duo excelled in their first proper overseas outing, underlining the team management's faith in leg-spin since July last year.
Earlier, South Africa won the toss and opted to bat. As expected, Aiden Markram came in for injured A B de Villiers and the hosts went in with only one spinner. India's playing eleven was along anticipated lines, with Ajinkya Rahane slated to bat at No. 4 for the first time since January 2016.
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A sell-out crowd was expected for this first match of the six-ODI series but the fans -- mostly Indian supporters -- only arrived in spurts on account of a working Thursday, building up gradually over the afternoon. This is the only game of the Indian tour in Durban.
They put on 30 runs for the opening wicket before Jasprit Bumrah (1/56) struck in the 8th over. He trapped Amla plumb lbw, albeit was lucky to have his front-foot only millimetres behind the line.
Just before this, India had a major injury scare when Virat Kohli hurt his knee while fielding in the 7th over. He struggled with his right leg for a while thereafter, and even went off to the Indian dugout to get attention from the physiotherapist.
Meanwhile, du Plessis began his innings in attacking fashion. He put on 53 runs off 46 balls with de Kock for the second wicket. India had brought on spin from the 11th over itself as Chahal exerted control over proceedings. However, the Proteas' batsmen attacked Pandya and he was expensive in his first spell.
The spinners took quick wickets thereafter and did not allow South Africa's partnerships to settle even as 100 came up in the 21st over. Aiden Markram (9) was caught off Chahal shortly after.
Then Yadav got into the act. He bowled J P Duminy (12) with one that kept low, whilst foxing David Miller (7) into a false shot as Kohli completed a smart forward-diving catch at short extra-cover.
Du Plessis reached his half-century off 54 balls and brought up his 50-partnership with Morris off 57 balls. South Africa recovered to reach 200/5 at the end of 40 overs.
Yadav returned for a final spell to bowl Morris in the 41st over. Du Plessis though stood tall and added 56 runs for the 7th wicket with Andile Phehlukwayo (26 not out). In doing so, he brought up his century off 101 balls.
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