They said the car targeted in the today's attack appeared to be headed to the province of Marib.
The officials spoke on condition of anonymity because they were not authorized to speak to the media.
US drone strikes have killed dozens of al-Qaida militants in Yemen as part of Washington's global war on terror.
Al-Qaida and the extremist Islamic State group have taken advantage of the chaos and lawlessness brought about by Yemen's ongoing civil war to expand their reach in the impoverished Arabian Peninsula nation.
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