Yogeeshwar handed over his resignation letter to Assembly Speaker K G Bopaiah at his office here.
However, Yogeeshwar, had to face the ire of BJP workers, who protested against his resignation and he was escorted out of the town by police, sources said.
Yogeeshwar, who defected to BJP from Congress, is expected to return to his parent party.
Rajugowda, the Small Scale Industries Minister, who also resigned from the ministry along wth Yogeeshwar yesterday, however, did not resign his assembly membership.