Saldana, 36, took to Twitter to inform that she will be taking care of her babies.
"Is anyone having a @Goldenglobes party? It's looking like popcorn on the couch along milk bottles for the little guys while the #globes are on for us," she said.
Last year, Saldana wowed at the star-studded awards show. She wore a black gown from Prabal Gurung's spring 2014 collection, which included embroidered Swarovski crystals.
The 'Guardians of the Galaxy' actress confirmed just last week that she and husband Marco Perego welcomed twin boys.