The 41-year-old actress portrays undead Sheila in the new Netflix show and said the new role gave her new-found confidence and inspiration after her marriage split from husband Will Kopelman, reported Contactmusic.
"It (TV show) came in the middle of this moment in my life, where I had let myself go due to personal circumstances, and I thought I could come alive with Sheila.
"It was a really great goal line for me, because as much as the weight loss... Everything's very subtle, it's attitudinal, it's empowerment, it's confidence (sic)," Barrymore said.
Barrymore split from art consultant Kopelman, the father of her two daughters Olive and Frankie, last April.