The pharmaceutical industry stands at crossroads with traditional business models becoming obsolete in today’s heavily disrupted marketplace. Although it may be too late to halt the decline of the traditional model by incremental adjustments or by steady evolution, it is certainly not too late to rethink how pharmaceutical companies can adapt and thrive in the face of shifting payer attitudes and patient empowerment.
A cursory glance at the current pharmaceutical industry might imply that all is well. However, there are two seismic shifts that are expected to disturb the industry status quo – the downward pressure on drug pricing and the shift from treatment to prevention and complete cure.
Deep diving into these shifts, KPMG’s recent white paper ‘Pharma Outlook 2030: From evolution to revolution’ looks at the potential 2030 scenario examining trends that are expected to have a dramatic impact going forward.
Downward pressure on pricing
With a change in the balance of power across the healthcare value chain, patients and governments will take centre stage, pressuring pharmaceutical companies to reduce prices; greater transparency around drug pricing has become the demand of the hour. The healthcare system is moving towards an outcome-based care where fees are expected to be dependent upon the success of drugs and procedures through measurable outcomes.
These market dynamics have led pharmaceutical companies to think of transformative ways that could replace traditional blockbuster drugs, increase innovation, and shift from physician-preferred models to patient-centric models.
From treatment to prevention, and beyond
The emergence of ground-breaking new therapies, advances in technology and the consumerisation of health through increased access to data by patients are expected to augment the shift from treatment of symptoms to prevention measures and complete cures by 2030. Patients are expected to play an important role in driving this change as they gain more access to data, understand their conditions better and get more involved in managing themselves/their curative process.
With this change, new players are also expected to enter the market, both from inside and outside the industry - putting the traditional business model under immense pressure.
Strategies for pharmaceutical companies
A few pharmaceutical companies have started to recognise the impact of the two major shifts discussed above, which upset the existing status quo and open the doors to new competition. The following strategies could help pharmaceutical companies to respond to the disruptions:
Embrace technology to increase efficiency and improve quality: Big data analytics, Internet of Things (IoT), artificial intelligence (AI) and machine learning are expected to shake the pharmaceutical industry with their immense potential. Companies across the value chain of the pharmaceutical industry can enhance competitiveness, develop new products and services, improve time to market, increase quality compliance and reduce cost by embracing technology. These measures could also help Indian pharmaceutical companies achieve output at par with international standards.
Move up the value chain through research and development (R&D): Over the last two decades, Indian pharmaceutical companies have acquired capabilities and skills in several pharma R&D areas, such as cost effective process development, custom synthesis and toxicology studies. These skill sets and higher spend on R&D could help them launch complex products in the Indian and international markets with better margins.
M&A and collaborations for value creation: Inorganic growth can help Indian pharma companies access new markets and enhance technological capabilities in developing new drugs. Collaborations in a wide variety of areas, such as R&D, manufacturing and marketing, can also help enhance value by reducing cost and increasing efficiency.
Focus on patient centricity to increase value proposition: As patients are moving from being recipients to participants, the pharma industry, sooner rather than later, needs to adopt a ‘patient-centric’ approach to drive growth. The pharma industry may need to innovate and reinvent to upgrade its multiple skills and organisation structure to keep pace with shifting end-to-end delivery system.
Develop skills for a VUCA (volatility, uncertainty, complexity and ambiguity) world: The pharmaceutical industry is operating in an environment where newer challenges are emerging due to changing demographics, active patients, strict regulations, globalisation, digital revolution, variations in products and services, etc. Companies need to improve their agility to respond to market disruptions quickly by adopting new business models that support shorter life cycle, share resources, support flexible outsourcing and rebalance ‘pull’ versus ‘push’ factors.
Emergence of three pharmaceutical archetypes
Utkarsh Palnitkar
Pharmaceutical companies can adapt to disruption through shifts in business models and refocus on new fields of play. However, even these changes are unlikely to generate the kind of growth and revenue that shareholders demand. Adopting the above-mentioned strategies can lead to complete organisational transformation that can help companies maintain influence and earnings. This situation could lead to three types of ‘archetype’, which are expected to prevail in the future pharmaceutical industry.
These three pharmaceutical archetypes are:
Active portfolio company: It is typically active in several therapeutic areas within its portfolio. A company is equipped to acquire and divest parts of its portfolio in a ‘plug-and-play’ fashion by being flexible and agile
The virtual value chain orchestrator: Companies that primarily own data and design platforms to provide solutions, such as guiding patients and supporting healthcare practitioners to provide tailored care and pharma companies to receive outcome-based payments. These platforms would be the new way to link supply with demand
The niche specialist: Small companies that focus on a single therapeutic area or disease, can look at the entire patient pathway from prevention to real cure
Currently, in India, we see that the portfolio decisions or focus areas of pharma companies already reflect some of these trends. We are also observing inorganic growth via acquisition, and growing portfolios as a strategy to combat downturns in income due to price control regime and regulatory scrutiny.
Action required by pharma leaders
To adapt to the emerging changes, pharma leaders need to take swift steps to get ahead of changes. CEOs may not be able to predict the future. However, they can test potential solutions in think-tanks or laboratories. CEOs can prepare for the future in a way by setting up fully independent, integrated Pharma 2030 experimental laboratories to test new archetypes and business models, and accordingly determine which new organisational capabilities are needed and, accordingly develop a balanced transition map. By preparing for this future now, leaders can reduce the risk of declining income, while creating new opportunities for growth.