Covid-19: Experts bat for mixing vaccines in the wake of BA.2.75 variant

Senior research fellow at Oxford say BA.2.75 has several mutations in the spike protein, two of which are unique to it when compared to its parent strain BA.2

Experts have backed heterologous boosting or mixing of vaccines for the booster dose in the wake of BA.2.75, a variant resulting from another major mutation in the Sars-CoV-2 virus that infects people with Covid-19.

Shahid Jameel, senior research fellow at Green Templeton College in Oxford University, told Business Standard that the BA.2.75 has several mutations in the spike protein, two of which are unique to it and are not found in its parent strain, BA.2. These two mutations are G446S and R493Q.

Jameel feels that G446S is one of the most potent sites of escape from antibodies made by current vaccines that