 "oxford, vaccine trials, coronavirus, covid-19")
With preparations underway for a possible vaccine-rollout by January, the Indian drug regulator is looking at the UK, which sources believe may give its nod to theOxfordCOVID-19vaccine next week, before deciding on giving emergencyuse authorisationto the Serum Institute that is manufacturing the shots here.
Once the UK drug regulator gives its approval to the Oxford vaccine, the expert committee on COVID-19 at the CDSCO will hold its meeting andthoroughly review the safety and immunogenicity data from the clinical evaluations conducted abroad and in India before granting any emergency authorisationfor the vaccine here, official sources said.
The process ofgranting emergency use approval for Bharat Biotech's COVID-19 vaccine 'Covaxin' may take time as its phase 3 trials are still underway, while Pfizer is yet to make a presentation.
"Going by this, Oxford vaccine 'Covishield' is likely to be the first to be rolled out in India," a source said.
Serum Institute of India (SII)last week also had submitted some additional data required by the Drug Controller General of India (DCGI), the sources said.
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BharatBiotech,SerumInstitute of India (SII) andPfizer hadapplied to the Drugs Controller General of India (DCGI) seeking emergency use authorisation for their COVID-19 vaccines early this month.
The subject expert committee (SEC) on COVID-19 of the Central Drugs Standard Control Organisation (CDSCO) on December 9 had sought additional safety and efficacydatafor COVID-19 vaccines of SII and Bharat Biotech after deliberating upon their applications.
The application by the Indian arm of US pharmaceutical firm Pfizer was not taken up for deliberation as the company had sought more time for making a presentation before the committee.
The Pfizer vaccine has already been approved by several countries including the UK, the US, and Bahrain.
While considering SII's application, the SEC had recommended that the firm should submit an updated safetydataof phase 2 and 3 clinical trials in the country, immunogenicitydatafrom the clinical trial in the UK and India, along with the outcome of the assessment of the UK Medicines and Healthcare products Regulatory Agency (MHRA) for grant of EUA.
As for Hyderabad-based Bharat Biotech, "after detailed deliberation, the committee recommended that the firm should present the safety and efficacydatafrom the ongoing phase 3 clinical trial in the country for further consideration", the SEC had said.
The Pune-based SII,the world'slargestvaccine manufacturer,has made a collaboration with the University of Oxford and AstraZeneca to manufacture the vaccine.
The SII has alreadymanufactured 40 million doses of the vaccine, under the at-risk manufacturing and stockpiling licence from the DCGI, officials recently had said.
(Only the headline and picture of this report may have been reworked by the Business Standard staff; the rest of the content is auto-generated from a syndicated feed.)
