Big Bang Theory finale: How plausible is Amy, Sheldon's asymmetry concept?

Science, especially physics, is a recurring theme in the show

After 12 successful seasons, “The Big Bang Theory” has finally come to a fulfilling end, concluding its reign as the longest running multicamera sitcom on TV.

If you’re one of the few who haven’t seen the show, this CBS series centers around a group of young scientists defined by essentially every possible stereotype about nerds and geeks. The main character, Sheldon (Jim Parsons), is a theoretical physicist. He is exceptionally intelligent, but also socially unconventional, egocentric, envious and ultra-competitive. His best friend, Leonard (Johnny Galecki), is an experimental physicist who, although more