In the autumn of 1817, a mysterious intestinal disease that had been endemic to the rural Ganges delta arrived in Calcutta, then the East India Company’s capital and a major centre for inter-Asian trade. The malady was associated with a variety of interconnected symptoms, among them lethargy, diarrhoea, vomiting, chills and abdominal pain. It came to be known as a ‘cholera’, one of several present on the Indian subcontinent, because it resembled a host of other diseases that caused those affected to forcefully expel fluids from their bodies.
As the contagion spread further afield—to British outposts in Burma, Sri Lanka and