High-dose Vitamin D supplements no better than low-dose, finds study

Low blood levels of vitamin D are tied to bone loss that can lead to falls and fractures. But taking vitamin D supplements in high doses showed no benefits over low-dose vitamin D, a randomised trial found.

The study, in the American Journal of Clinical Nutrition, included 379 British men and women whose average age was 75. They were divided into three groups and given monthly doses of vitamin D, equivalent to 400, 800 and 1,600 IU a day; there was no placebo group. The groups were well matched at the start for vitamin D blood levels, bone mineral density, height,