Every death from malaria is a tragedy. But many infections can be prevented. This is particularly true for holidaymakers, travellers, or people visiting their families in malaria endemic areas. All they need to do is follow some very simple rules. Malaria is a complicated disease – I should know, after studying it for more than 30 years – but the solutions to avoiding and treating it can be as simple as “ABCD”. If the basics of prevention are followed, a great deal of unnecessary illness and mortality can be avoided.