The benchmark indices settled the Tuesday's session lower tracking European markets which fell ahead of British Prime Minister Theresa May's speech on Brexit due later in the day.
Investors will scrutinise May's speech for clues to whether she plans to prioritise immigration controls in a hard Brexit that some say could hurt UK's economy.
The market opened higher in the early trade thanks to a breakthrough on the dual control of Goods and Services Tax (GST) between Centre and the state governments in a metting on Monday, but pared gains soon after.
The S&P BSE Sensex closed at 27,235, down