The Kandahar airport was attacked by Taliban insurgents, triggering several explosions and a major gunbattle between security personnel and the militants.
According to the Express Tribune, a number of suicide attackers entered the airport ground and opened fire, in which several civilians and passengers became trapped.
"Several insurgents (have) taken up position inside a school and (are) firing at the airport," said Sameem Khpalwak, a spokesperson for the local governor.
The episode occurred on the eve of Afghan President Ashraf Ghani's high-profile visit to Islamabad for a regional conference.
The attack comes after an earlier incident in which two suicide bombers were killed following their attack on a police station in Kandahar, which happens to be one of the Taliban strongholds.