A van moved down a number of pedestrians on the London Bridge, injuring several.
Armed police and emergency vehicles have been dispatched to the scene, where there were unconfirmed reports of bodies lying on the ground, The Independent reported.
The London Bridge station has been closed "at the request of police" following what has been described as a "major police incident".
The Met Police said on Twitter: "We are dealing with an incident on London Bridge, when we have more information we will update this Twitter feed."
England has been on the edge since May 22, when a suicide bomber killed 22 people at an Ariana Grande concert at the Manchester Arena.
Earlier on March 24, London was struck by a terror attack that killed four people and left dozens injured in the city's deadliest attack in over a decade.
52-year-old Khalid Masood mowed down people injuring as many as 40 on the Westminster Bridge in a terror attack on London and stabbed a police officer to death as he tried to enter the U.K. Parliament.
The ISIS had claimed responsibility for the attack, saying that a "soldier of the caliphate" carried out the atrocity in Westminster.
The terror organisation said that the attacker followed a call to attack civilians and security forces in countries allied to the U.S.-led coalition bombing the ISIS territories in Syria and Iraq.
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