Ukrainian riot police took on anti-government protestors in Kiev early Wednesday, after the bloodiest outburst of violence in nearly three months of demonstrations.
The police surrounded the Independence Square, the main site where protestors had camped Tuesday, and dismantled barricades and dispersed demonstrators with stun grenades and water cannon.
At least 14 protestors and seven policemen were killed during the violence, Xinhua reported.
Tuesday's unrest marked the latest wave of clashes between demonstrators and riot police in the political standoff, which began last November with the Ukrainian government's decision to backtrack on the country's European integration that angered many Ukrainians.
The demonstrations turned violent Jan 19, when radical activists attacked riot police with fireworks and petrol bombs, causing casualties.
In New York, UN spokesperson Martin Nesirky said Secretary-General Ban Ki-moon expressed grave concern about renewed violence and fatalities in Kiev.
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The UN cheif closely followed the developments in Ukraine and "reiterates his appeal to all concerned to act with restraint in order to avoid any further violence", Nesirky said.
US Vice President Joe Biden also called on Ukrainian President Viktor Yanukovych to pull back government forces and exercise "maximum" restraint in the current crisis.
Biden called Yanukovych Tuesday to express "grave" concern regarding the crisis on the streets of Kiev, said a White House statement and added that Biden underscored the urgency of immediate dialogue with opposition leaders.
In Paris, French Foreign Minister Laurent Fabius condemned the fresh wave of violence in Ukraine, urging all parties to exercise restraint and resume dialogue.
"I condemn the resumption of violence in Kiev and the indiscriminate use of force which resulted in several deaths. I call on all parties to exercise the utmost restraint and to immediately resume dialogue," Fabius said in a statement.
Meanwhile, Ukrainian opposition leader Vitali Klitschko said Yanukovych has told opposition leaders that he would not call off the police assault on the opposition's main protest camp on the Independence Square.
"Yanukovych said that there is only one option... to clear Maidan and that everyone has to go home," Klitschko told independent Hromadske TV after meeting the president.
Responding to concerns and criticisms, Ukraine's acting Foreign Minister Leonid Kozhara asked the international community to make an objective evaluation of the recent violence.
"We call on foreign governments and international organizations to make a fair and impartial assessment of the situation in Ukraine," Kozhara was quoted by the foreign ministry's press office as saying.
He voiced his hope that the international community would "strongly condemn" the illegal actions of radical activists, who initiated a new wave of "violence and lawlessness" in Ukraine.