Gennaro Gattuso, former Italy and AC Milan midfielder, was Tuesday placed under investigation for match-fixing, Xinhua reported.
Gattuso and retired Milan and Lazio player Cristian Brocchi were allegedly part of a ring that fixed Series A and other Italian matches at the end of the 2010-11 season.
According to the ANSA news agency, four others - Salvatore Spadaro, Francesco Bazzani, Cosimo Rinci and Fabio Quadri - were arrested for allegedly helping connect fixers to players.
Police said in a statement that the arrests were carried out in Milan, Bologna, Rimini and Messina.
The Gazzetta dello Sport reported that AC Milan matches against Lazio, Chievo Verona and Bari in February and March 2011 were under investigation, plus games involving Juventus and Inter Milan.
AC Milan won their last Series A title in 2011.