Samuels has been ruled out of the remainder of the tournament, and the Twenty20 Big Bash League technical committee approved the change Tuesday.
Hales, 24, has been a regular member of the England T20 International squad over the past 18 months which included the 2012 ICC World Twenty20 and recent tour of India. He averages 34.83 at a strike rate of 127.43 in 14 T20Is.
Hales will join the Renegades squad in Sydney in time for their last round match against the Sydney Sixers Wednesday night.
